Scientists at Newcastle University have shed new light on how the brain tunes in to relevant information.
Publishing in Neuron, the team reveal the interplay of brain chemicals which help us pay attention in work funded by the Wellcome Trust and BBSRC.
By changing the way neurons respond to external stimuli we improve our perceptual abilities. While these changes can affect the strength of a neuronal response, they can also affect the fidelity of that response.
Lead author Alex Thiele, Professor of Visual Neuroscience explains: “When you communicate with others, you can make yourself better heard by speaking louder or by speaking more clearly. Neurons appear to do similar things when we’re paying attention. They send their message more intensely to their partners, which compares to speaking louder. But more importantly, they also increase the fidelity of their message, which compares to speaking more clearly.
“Our earlier work has shown that attention is able to affect the intensity of responses – in effect the loudness - by means of the brain chemical acetylcholine. Now we have shown that the fidelity of the response is altered by a different brain chemical system.”
In the paper, the team reveal that the quality of the response is altered by means of glutamate coupling to NMDA receptors (a molecular device that mediates communication between neurons). Carried out in a primate model, these studies for the first time isolate different attention mechanisms at the receptor level.
The research builds on the team’s previous studies and has potentially significant implications not only for our understanding of how our brains work but also give an insight into conditions such as schizophrenia, Alzheimer’s disease and attention deficit disorder, and may aid in the development of treatments for them.
KELSIE I MISS YOU TOO!!!!!!!!!!!
And I get to see you too this weekend and that makes me super happy. I also want a big hug from you! This weekend is going to be awesome and I’m super excited to spend some time in Boston and see Fall Out Boy finally!
Can’t wait to see you!! I hope you’ve had a good week at home so far, and that you’re prepared for some triforce shenanigans this weekend. =] See you soooooooon!
HALEY WHY DID YOU LEAVE ME ALONE FOR A WEEK?!?!?!
I AM SO BORED. AND I MISS YOU SO MUCH!!!!!!!! I AM GOING TO BEAR HUG YOU WHEN I SEE YOU TOMORROW.
I am so excited for Fall Out Boy I can barely stand it. This is like how you would react when you finally see McFly live. This is almost 10 years worth of band love that’s been bottled up and it will be let loose Sunday. CANNOT WAIT!!!
Also while I have been by my lonesome I have started watching Supernatural and Game of Thrones simultaneously. Probably a poor decision on my part but I don’t care. Supernatural is slowly ripping me to pieces. I’m on episode three of season two and John is dead and I was not emotionally prepared for all of the daddy issues and feels and tears. And I cannot decide which brother I relate to more. On our long drive tomorrow we shall have a more in depth conversation about this. But know that I have been a mess because of this god damn show.
Game of Thrones is really good and I wish my internet wasn’t being such a shit and would load the links so I could watch more. I switched to GoT because watching Supernatural at night is not a thing I can do. I get like hella creeped out with the ghost and spirt episodes. Steve made fun of me for it, but I do not do well with scary things. Creepy demons I can handle. Ghosts scare the fuck out of me, especially when everyone is asleep and the sky is eery and rainy and just not pleasant. I’m a baby, I know.
Any who I miss you and I can’t wait to see you and hear all about your wonderful cruise. Also I think we need to brings these notes back into style because I forgot how fun it is to write things and gif hunt. =] Toodles!
Pohutukawa Residence / Herbst Architects
1937 - Snow White and the Seven Dwarves
1940 - Fantasia
1940 - Pinocchio
1941 - Dumbo
1941 - The Reluctant Dragon
1942 - Bambi
1942 - Saludos Amigos
1943 - Victory Through Air Power
1945 - The Three Caballeros
1946 - Make Mine Music
1946 - Song of the South
1947 - Fun and Fancy Free
1948 - Melody Time
1949 - The Adventures Of Ichabod and Mr. Toad
1950 - Cinderella
1951 - Alice in Wonderland
1953 - Peter Pan
1954 - 20,000 Leagues Under the Sea
1955 - Lady and the Tramp
1957 - Old Yeller
1959 - Darby O’Gill and the Little People
1959 - Sleeping Beauty
1960 - Swiss Family Robinson
1961 - 101 Dalmatians
1963 - The Sword in the Stone
1964 - Mary Poppins
1965 - That Darn Cat
1967 - The Jungle Book
1968 - The Love Bug
1970 - The Aristocats
1971 - Bedknobs and Broomsticks
1971 - The Million Dollar Duck
1973 - Robin Hood
1974 - Herbie Rides Again
1977 - Pete’s Dragon
1977 - The Many Adventures of Winnie the Pooh
1977 - The Rescuers
1981 - The Fox and the Hound
1982 - A Disney Christmas Gift
1985 - The Black Cauldron
1986 - The Great Mouse Detective
1988 - Oliver & Company
1988 - Who Framed Roger Rabbit
1989 - The Little Mermaid
1990 - Ducktales The Movie - Treasure of the Lost Lamp
1990 - The Rescuers Down Under
1991 - Beauty and the Beast
1993 - The Nightmare Before Christmas
1994 - Aladdin -The Return of Jafar
1994 - Aladdin
1994 - The Lion King
1995 - A Goofy Movie
1995 - Pocahontas
1995 - Toy Story
1996 - Aladdin and the King of Thieves
1996 - James and the Giant Peach
1996 - The Hunchback of Notre Dame
1997 - Beauty and the Beast - The Enchanted Christmas
1997 - Hercules
1997 - Winnie The Pooh’s Most Grand Adventure
1998 - A Bug’s Life
1998 - Belle’s Magical World
1998 - Mulan
1998 - Pocahontas II - Journey to a New World
1998 - The Lion King 2 - Simba’s Pride
1999 - Mickey’s Once Upon A Christmas
1999 - Tarzan
1999 - Toy Story 2
1999 - Winnie The Pooh-Seasons of Giving
2000 - An Extremely Goofy Movie
2000 - Buzz Lightyear Of Star Command, The Adventure Begins
2000 - Dinosaur
2000 - Fantasia 2000
2000 - The Emperor’s New Groove
2000 - The Little Mermaid 2-Return to the Sea
2000 - The Tigger Movie
2001 - Atlantis The Lost Empire
2001 - Lady And The Tramp II - Scamp’s Adventure
2001 - Mickey’s Magical Christmas-Snowed In at the House of Mouse
2001 - Monsters, Inc.
2002 - Cinderella II - Dreams Come True
2002 - Lilo And Stitch
2002 - Mickey’s House of Mouse - The Villains
2002 - Return to Never Land
2002 - Tarzan & Jane
2002 - The Hunchback of Notre Dame II
2002 - Treasure Planet
2002 - Winnie the Pooh-A Very Merry Pooh Year
2003 - 101 Dalmatians 2 - Patch’s London Adventure
2003 - Atlantis 2 Milo’s Return
2003 - Brother Bear
2003 - Finding Nemo
2003 - Kim Possible - A Stitch In Time
2003 - Piglet’s Big Movie
2003 - Stitch! The Movie
2003 - The Jungle Book 2
2004 - Home On The Range
2004 - Kim Possible - The Villain Files
2004 - Mickey Donald Goofy-The Three Musketeers
2004 - Mickeys Twice Upon a Christmas
2004 - The Incredibles
2004 - The Lion King 1-1.5 - Hakuna Matata
2004 - Winnie the Pooh - Springtime With Roo
2005 - Chicken Little
2005 - Disney’s Christmas Favourites
2005 - Kim Possible - So The Drama
2005 - Kronk’s New Groove
2005 - Lilo and Stitch 2 - Stitch has a Glitch
2005 - Pooh’s Heffalump Movie
2005 - Tarzan II
2006 - Bambi II
2006 - Brother Bear 2
2006 - Cars
2006 - Leroy & Stitch
2006 - The Fox and the Hound 2
2007 - Cinderella III - A Twist in Time
2007 - Disney Princess Enchanted Tales - Follow Your Dreams
2007 - Enchanted
2007 - Meet The Robinsons
2008 - Bolt
2008 - The Little Mermaid - Ariel’s Beginning
2008 - Tinker Bell
2008 - Wall-E
I’ve been waiting for this gifset lol
I felt like that girl all day today…
Eddy my boyyyy
Do you ever just suddenly remember how simple the Winchester’s lives were back in Season 1
i fell in love with him like ketchup falls out of a bottle: slowly, and then all at once.
oh my god you managed to one up john green.
Dylan O’Brien visits with Movie Fanatic to talk up The Internship
we don’t need to ask for directions, helen.